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Miravirsen

Miravirsen is an experimental drug for the treatment of hepatitis C, being developed by Santaris Pharma. As of 2017 it was in Phase II clinical trials. Miravirsen was given subcutaneously in early clinical trials in 2017. It is antisense to human ...

                                               

Embryonal rhabdomyosarcoma

Embryonal rhabdomyosarcoma is a rare histological form of cancer of connective tissue wherein the mesenchymally-derived malignant cells resemble the primitive developing skeletal muscle of the embryo. It is the most common soft tissue sarcoma occ ...

                                               

Alveolar rhabdomyosarcoma

Alveolar rhabdomyosarcoma is a sub-type of the rhabdomyosarcoma soft tissue cancer family whose lineage is from mesenchymal cells and are related to skeletal muscle cells. ARMS tumors resemble the alveoli tissue that can be found in the lungs. Tu ...

                                               

Low-grade fibromyxoid sarcoma

Low-grade fibromyxoid sarcoma is a rare type of low grade sarcoma first described by Harry Evans in 1987. It is characterized by a long and indolent clinical course and the possibility of local recurrence or distant metastases in a subset of pati ...

                                               

Renal anaplastic sarcoma

Renal anaplastic sarcoma is a rare tumour of the kidney. By 2017 about 25 cases have been reported. This tumour occurs in children and young adults and is more common in females than males. Due to its rarity, its natural history is not well under ...

                                               

Gastrointestinal cancer

Gastrointestinal cancer refers to malignant conditions of the gastrointestinal tract and accessory organs of digestion, including the esophagus, stomach, biliary system, pancreas, small intestine, large intestine, rectum and anus. The symptoms re ...

                                               

Appendix cancer

Appendix cancer are very rare cancers of the vermiform appendix. Gastrointestinal stromal tumors rare tumors with malignant potential. Primary lymphomas can occur in the application. Breast cancer, colon cancer, and cancers of the female genital ...

                                               

Duodenal cancer

Duodenal cancer is a cancer in the first section of the small intestine known as the duodenum. Cancer of the duodenum is relatively rare compared to stomach cancer and colorectal cancer. Its histology is usually adenocarcinoma. FAP familial adeno ...

                                               

Esophageal cancer

Esophageal cancer is cancer arising from the esophagus - the food pipe that runs between the throat and the stomach. Symptoms often include difficulty in swallowing and weight loss. Other symptoms may include pain when swallowing, a hoarse voice, ...

                                               

Gastric lymphoma

Primary gastric lymphoma is an uncommon condition, accounting for less than 15% of gastric malignancies and about 2% of all lymphomas. However, the stomach is a very common extranodal site for lymphomas. It is also the most common source of lymph ...

                                               

Gastrointestinal stromal tumor

Gastrointestinal stromal tumors are the most common mesenchymal neoplasms of the gastrointestinal tract. GISTs arise in the smooth muscle pacemaker interstitial cell of Cajal, or similar cells. They are defined as tumors whose behavior is driven ...

                                               

Goblet cell carcinoid

The goblet cell carcinoid is a rare biphasic gastrointestinal tract tumour that consists of a neuroendocrine component and a conventional carcinoma, histologically arising from Paneth cells.

                                               

Intraductal papillary mucinous neoplasm

Intraductal papillary mucinous neoplasm is a type of tumor that can occur within the cells of the pancreatic duct. IPMN tumors produce mucus, and this mucus can form pancreatic cysts. Although intraductal papillary mucinous neoplasms are benign t ...

                                               

Linitis plastica

Linitis plastica is a widely used term for Brintons disease, a morphological variant of diffuse stomach cancer. In some texts, the term is also used to describe the condition of a rigid, non-distensible stomach which may be caused by a non-malign ...

                                               

Oesophagogastric junctional adenocarcinoma

Oesophagogastric junctional adenocarcinoma is a cancer of the lower part of the oesophagus, often linked to a Barretts oesophagus. The incidence of adenocarcinoma of the esophagus hub is rapidly growing in Western countries, in contrast to reduci ...

                                               

Pancreatic cancer

Pancreatic cancer arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass. These cancerous cells have the ability to invade other parts of the body. There are a number of types of ...

                                               

Poorly cohesive gastric carcinoma

Poorly cohesive gastric carcinoma is a malignant tumour of epithelial origin, characterized by diffuse distribution of tumour cells, isolated from each other or in small groups. According to the recently approved classification of tumors of the w ...

                                               

Small intestine cancer

Small intestine cancer is a cancer of the small intestine. It is relatively rare compared to other gastrointestinal malignancies such as gastric cancer and colorectal cancer. Small bowel cancer can be divided into cancer of the duodenum the first ...

                                               

Anaplastic thyroid cancer

Anaplastic thyroid cancer, also known as anaplastic thyroid carcinoma, is an aggressive form of thyroid cancer characterized by uncontrolled growth of cells in the thyroid gland. This form of cancer generally carries a very poor prognosis due to ...

                                               

Follicular thyroid cancer

Follicular thyroid cancer accounts for 15% of thyroid cancer and occurs more commonly in women over 50 years of age. Thyroglobulin can be used as a tumor marker for well-differentiated follicular thyroid cancer. Follicular cells are the thyroid c ...

                                               

Medullary thyroid cancer

Medullary thyroid cancer is a form of thyroid carcinoma which originates from the parafollicular cells, which produce the hormone calcitonin. Medullary tumors are the third most common of all thyroid cancers and together make up about 3% of all t ...

                                               

Papillary thyroid cancer

Papillary thyroid cancer or papillary thyroid carcinoma is the most common type of thyroid cancer, representing 75 percent to 85 percent of all thyroid cancer cases. It occurs more frequently in women and presents in the 20–55 year age group. It ...

                                               

Squamous-cell thyroid carcinoma

Squamous-cell thyroid carcinoma is rare malignant neoplasm of thyroid gland which shows tumor cells with distinct squamous differentiation. The incidence of SCTC is less than 1% out of thyroid malignancies.

                                               

Thyroid adenoma

A thyroid adenoma may be clinically silent "cold" adenoma, or it may be a functional tumor, producing excessive thyroid hormone "warm" or "hot" adenoma. In this case, it may result in symptomatic hyperthyroidism, and may be referred to as a toxic ...

                                               

Anaplastic carcinoma

Anaplastic carcinoma is a general term for a malignant neoplasm arising from the uncontrolled proliferation of transformed cells of epithelial origin, or showing some epithelial characteristics, but that reveal no cytological or architectural fea ...

                                               

Fetal adenocarcinoma

Fetal adenocarcinoma of the lung is a rare subtype of pulmonary adenocarcinoma that exhibits tissue architecture and cell characteristics that resemble fetal lung tissue upon microscopic examination. It is currently considered a variant of solid ...

                                               

Lewis lung carcinoma

Lewis lung carcinoma is a tumor that spontaneously developed as an epidermoid carcinoma in the lung of a C57BL mouse. It was discovered in 1951 by Dr. Margaret Lewis of the Wistar Institute and became one of the first transplantable tumors.

                                               

Metaplastic carcinoma

Metaplastic carcinoma, otherwise known as metaplastic carcinoma of the breast, is a heterogeneous group of cancers that exhibit varied patterns of metaplasia and differentiation along multiple cell lines. This rare and aggressive form of breast c ...

                                               

Primary peritoneal carcinoma

Primary peritoneal cancer or carcinoma is also known as serous surface papillary carcinoma, primary peritoneal carcinoma, extra-ovarian serous carcinoma, primary serous papillary carcinoma, psammomacarcinoma. It was historically classified under ...

                                               

Sarcomatoid carcinoma

Sarcomatoid carcinoma, sometimes referred to as pleomorphic carcinoma, is a relatively uncommon form of cancer whose malignant cells have histological, cytological, or molecular properties of both epithelial tumors and mesenchymal tumors. It is b ...

                                               

Blastic plasmacytoid dendritic cell neoplasm

Blastic plasmacytoid dendritic cell neoplasm is a rare hematologic malignancy. It was initially regarded as a form of lymphocyte-derived cutaneous lymphoma and alternatively named CD4+CD56+ hematodermic tumor, blastic NK cell lymphoma, and agranu ...

                                               

Plasma cell dyscrasias

Plasma cell dyscrasias are a spectrum of progressively more severe monoclonal gammopathies in which a clone or multiple clones of pre-malignant or malignant plasma cells over-produce and secrete into the blood stream a myeloma protein, i.e. an ab ...

                                               

Smouldering myeloma

Smouldering myeloma, is a disease classified as intermediate in a spectrum of step-wise progressive diseases termed plasma cell dyscrasias. In this spectrum of diseases, a clone of plasma cells secreting monoclonal paraprotein causes the relative ...

                                               

Tumors of the hematopoietic and lymphoid tissues

Tumors of the hematopoietic and lymphoid tissues or tumours of the haematopoietic and lymphoid malignancies are tumors that affect the blood, bone marrow, lymph, and lymphatic system. Because these tissues are all intimately connected through bot ...

                                               

International Prognostic Scoring System

The International Prognostic Scoring System, published in 1997, is used by many doctors to help assess the severity of a patients myelodysplastic syndrome. Based on the IPSS score, the patients history, and his/her personal observations, the phys ...

                                               

Myeloproliferative neoplasm

The myeloproliferative neoplasms, previously myeloproliferative diseases, are a group of diseases of the bone marrow in which excess cells are produced. They are related to, and may evolve into, myelodysplastic syndrome and acute myeloid leukemia ...

                                               

Refractory cytopenia of childhood

Refractory cytopenia of childhood is a subgroup of myelodysplastic syndrome, having been added to the World Health Organization classification in 2008. Before then, RCC cases were classified as childhood aplastic anemia. RCC is the most common fo ...

                                               

Acinar adenocarcinoma

Acinar adenocarcinoma is a histological subtype of gland-forming cancer that is diagnosed when cuboidal and/or columnar shaped malignant cells in the neoplastic tissue form acini and tubules. It is a common form of cancer occurring in the lung an ...

                                               

Selenium and Vitamin E Cancer Prevention Trial

The Selenium and Vitamin E Cancer Prevention Trial, or SELECT, was a clinical trial conducted with the goal of determining whether vitamin E and selenium supplements could prevent prostate cancer. Enrollment for the trial began in 2001 and ended ...

                                               

SLC45A3

Solute carrier family 45 member 3, also known as prostate cancer-associated protein 6 or prostein, is a protein that in humans is encoded by the SLC45A3 gene. SLC45A3 is expressed in a prostate-specific manner in normal tissues and at much lower ...

                                               

VCaP

VCaP cells are a cell line of human prostate cancer commonly used in the field of oncology. The tissue was harvested at autopsy from a metastatic lesion to a lumbar vertebrae of a 59 year old Caucasian male with hormone refractory prostate cancer ...

                                               

Anaplastic astrocytoma

Anaplastic astrocytoma is a rare WHO grade III type of astrocytoma, which is a type of cancer of the brain. In the United States, the annual incidence rate for Anaplastic astrocytoma is 0.44 per 100.000 people

                                               

Astrocytoma

Astrocytomas are a type of Brain tumor. They originate in a particular kind of glial cells, star-shaped brain cells in the cerebrum called astrocytes. This type of tumor does not usually spread outside the brain and spinal cord and it does not us ...

                                               

Brain metastasis

A brain metastasis is a cancer that has metastasized to the brain from another location in the body and is therefore considered a secondary brain tumor. The metastasis typically shares a cancer cell type with the original site of the cancer. Meta ...

                                               

Central neurocytoma

Central neurocytoma is an extremely rare, ordinarily benign intraventricular brain tumour that typically forms from the neuronal cells of the septum pellucidum. The majority of central neurocytomas grow inwards into the ventricular system forming ...

                                               

Choroid plexus carcinoma

A choroid plexus carcinoma is a type of choroid plexus tumor that affects the choroid plexus of the brain. It is considered the worst of the three grades of chord plexus tumors, having a much poorer prognosis than choroid atypical plexus papillom ...

                                               

Choroid plexus papilloma

Choroid plexus papilloma, also known as papilloma of the choroid plexus, is a rare benign neuroepithelial intraventricular WHO grade I lesion found in the choroid plexus. It leads to increased cerebrospinal fluid production, thus causing increase ...

                                               

Dysembryoplastic neuroepithelial tumour

Dysembryoplastic neuroepithelial tumour is a type of brain tumor. Most commonly found in the temporal lobe, DNTs have been classified as benign tumours. These are glioneuronal tumours comprising both glial and neuron cells and often have ties to ...

                                               

Giant-cell glioblastoma

The giant-cell glioblastoma is a histological variant of glioblastoma, presenting a prevalence of bizarre, multinucleated giant cells. He sometimes shows a wide network of stromal and reticulin is a high frequency of mutations in the gene ТР53. S ...

                                               

Glioma

A glioma is a type of tumor that starts in the glial cells of the brain or the spine. Gliomas comprise about 30 percent of all brain tumors and central nervous system tumours, and 80 percent of all malignant brain tumours.

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Pino - logical board game which is based on tactics and strategy. In general this is a remix of chess, checkers and corners. The game develops imagination, concentration, teaches how to solve tasks, plan their own actions and of course to think logically. It does not matter how much pieces you have, the main thing is how they are placement!

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