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Tetratricopeptide repeat 39A

Tetratricopeptide repeat 39A is a human protein encoded by the TTC39A gene. TTC39A is also known as DEME-6, KIAA0452, and c1orf34. The function of TTC39A is currently not well understood. The main feature within tetratricopeptide repeat 39A is th ...

                                               

TGFBR3

Betaglycan also known as Transforming growth factor beta receptor III, is a cell-surface chondroitin sulfate / heparan sulfate proteoglycan &gt, 300 kDa in molecular weight. Betaglycan binds to various members of the TGF-beta superfamily of ligan ...

                                               

Thiamine transporter 1

Thiamine transporter 1, also known as thiamine carrier 1 or solute carrier family 19 member 2 is a protein that in humans is encoded by the SLC19A2 gene. SLC19A2 is a thiamine transporter. Mutations in this gene cause thiamine-responsive megalobl ...

                                               

Thrombopoietin receptor

The thrombopoietin receptor also known as the myeloproliferative leukemia protein or CD110 is a protein that in humans is encoded by the MPL oncogene.

                                               

Thrombospondin 3

Thrombospondin-3 is a protein that in humans is encoded by the THBS3 gene. The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate intercellular and cell-to-matr ...

                                               

Tissue factor

Tissue factor, also called platelet tissue factor, factor III, or CD142, is a protein encoded by the F3 gene, present in subendothelial tissue and leukocytes. Its role in the clotting process is the initiation of thrombin formation from the zymog ...

                                               

TLR5

Toll-like receptor 5, also known as TLR5, is a protein which in humans is encoded by the TLR5 gene. It is a member of the toll-like receptor family. TLR5 is known to recognize bacterial flagellin from invading mobile bacteria. It has been shown t ...

                                               

Tm2 domain containing 1

The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G pro ...

                                               

TMEM50A

Transmembrane protein 50A is a protein that in humans is encoded by the TMEM50A gene. This gene is located in the RH gene locus, between the RHD and RHCE Gene. The function of its protein product is unknown, but its sequence of potential transmem ...

                                               

TMEM59

Transmembrane protein 59 is a protein that in humans is encoded by the TMEM59 gene. TMEM59 is a membrane bound protein that is localized in the Golgi apparatus. The exact functions of TMEM59 is not known, but it is shown that the expression of TM ...

                                               

TMEM63A

Transmembrane protein 63A is a protein that in humans is encoded by the TMEM63A gene. The mature human protein is approximately 92.1 kilodaltons, with a relatively high conservation of mass in orthologs. The protein contains eleven transmembrane ...

                                               

TMEM69

TMEM69, also known as Transmembrane protein 69, is a protein that in humans is encoded by the TMEM69 gene. A notable feature of the protein encoded by TMEM69 is the presence of five transmembrane segments.

                                               

TNFAIP8L2

TNF alpha induced protein 8 like 2, also known as TIPE2, is a protein that in humans is encoded by the TNFAIP8L2 gene. It is preferentially expressed in human myeloid cell types and serves as an immune checkpoint regulator of inflammation and met ...

                                               

TNFRSF18

Tumor necrosis factor receptor superfamily member 18 also known as activation-inducible TNFR family receptor or glucocorticoid-induced TNFR-related protein is a protein that in humans is encoded by the TNFRSF18 gene. GITR is currently of interest ...

                                               

TNFSF18

Tumor necrosis factor ligand superfamily member 18 is a protein that in humans is encoded by the TNFSF18 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor TNF family of ligand. This cytokine is a ligan ...

                                               

TNNI1

Troponin I, slow skeletal muscle is a protein that in humans is encoded by the TNNI1 gene. It is a tissue-specific subtype of troponin I, which in turn is a part of the troponin complex. Gene TNNI1, troponin I type 1 skeletal muscle, slowly, also ...

                                               

TNNT2

Cardiac muscle troponin T is a protein that in humans is encoded by the TNNT2 gene. Cardiac TnT is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction ...

                                               

TOR1AIP1

Torsin-1A-interacting protein 1 is a protein that in humans is encoded by the TOR1AIP1 gene. More commonly known as lamina associated polypeptide 1, it is a type II integral membrane protein that resides in the inner nuclear membrane. The luminal ...

                                               

TP53BP2

Apoptosis-stimulating of p53 protein 2 also known as Bcl2-binding protein and tumor suppressor p53-binding protein 2 is a protein that in humans is encoded by the TP53BP2 gene. Multiple transcript variants encoding different isoforms have been fo ...

                                               

TRAF3IP3

Model organisms have been used in the study of TRAF3IP3 function. A conditional knockout mouse line, called Traf3ip3 tm1aKOMPWtsi was generated as part of the International Knockout Mouse Consortium program - a high-throughput mutagenesis project ...

                                               

TRAF5

The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor TRAF protein family and contains a meprin and TRAF homology MATH domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF p ...

                                               

Transmembrane protein 53

Transmembrane protein 53, or TMEM53, is a protein that is encoded on chromosome 1 in humans. It has no paralogs but is predicted to have many orthologs across eukaryotes.

                                               

Trichohyalin

In 1903 the name" trichohyalin” was assigned to the granules of the inner root sheath IRS of hair follicles discovered by H. Voerner. In 1986 the name was reassigned to a protein isolated from sheep wool follicles.

                                               

TRIM11

Tripartite motif-containing protein 11 is a protein found in humans that is encoded by the TRIM11 gene. The protein encoded by this gene is a member of the tripartite motif trim family. The trim motif includes three zinc-binding domains, ring, B- ...

                                               

TRIM45

tripartite motif containing 45, also known as TRIM45, is a human gene. This gene encodes a member of the tripartite motif family. The encoded protein may function as a "transcriptional repressor of the mitogen-activated protein kinase path. Alter ...

                                               

TRIM63

E3 ubiquitin-protein ligase TRIM63 is an enzyme that in humans is encoded by the TRIM63 gene. This gene encodes a member of the family of ring zinc finger protein found in striated muscle and iris. The product of this gene is localized to Z-lines ...

                                               

TRIT1

tRNA isopentenyltransferase, mitochondrial is an enzyme that in humans is encoded by the TRIT1 gene. It catalyzes the addition of an isopentenyl group from dimethylallyl diphosphate onto adenosine residue 37 of certain tRNA molecules.

                                               

Tropomodulin 4

This gene encodes a muscle-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein ...

                                               

Tropomyosin 3

Tropomyosin alpha-3 chain is a protein that in humans is encoded by the TPM3 gene. This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskelet ...

                                               

TSEN15

tRNA-splicing endonuclease subunit Sen15 is an enzyme that in humans is encoded by the TSEN15 gene. tRNA splicing is a fundamental process for growth and cell division. SEN15 is a subunit of the RNA splicing endonuclease, which catalyzes the remo ...

                                               

TSHB

Thyrotropin-stimulating hormone TSH is a noncovalently linked glycoprotein heterodimer and is part of a family of pituitary hormones containing a common alpha subunit TSHA and a unique beta subunit this protein that confers specificity.

                                               

TSPAN2

Tetraspanin-2 is a protein that in humans is encoded by the TSPAN2 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that a ...

                                               

TTC4

Tetratricopeptide repeat protein 4 is a protein that in humans is encoded by the TTC4 gene. A 34-amino acid tetratricopeptide repeat TPR motif found in many proteins and may mediate protein-protein and protein-membrane interactions.

                                               

TTF2

Transcription termination factor 2 is a protein that in humans is encoded by the TTF2 gene. This gene encodes a member of the SWI2 / SNF2 family of proteins that play an important role in altering protein-DNA interactions. The encoded protein has ...

                                               

UBE4B

Ubiquitin conjugation factor E4 B is a protein that in humans is encoded by the UBE4B gene. Modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination ...

                                               

UBIAD1

UbiA prenyltransferase domain-containing protein 1 also known as transitional epithelial response protein 1 is a protein that in humans is encoded by the UBIAD1 gene. Recent data indicate that ubiad1 has enzymatic activity in the path vitamin K r ...

                                               

UBXD5

This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several h ...

                                               

UCK2

Uridine-cytidine kinase 2 is an enzyme that in humans is encoded by the UCK2 gene. The protein encoded by this gene catalyzes the phosphorylation of uridine and cytidine to uridine-monophosphate, cytidine monophosphate UMP and KC, respectively. T ...

                                               

UDP-glucose 4-epimerase

The enzyme UDP-glucose 4-epimerase, also known as UDP-galactose 4-epimerase or GALE, is a homodimeric epimerase found in bacterial, fungal, plant, and mammalian cells. This enzyme performs the final step in the Leloir pathway of galactose metabol ...

                                               

UHMK1

UHMK1 is highly expressed in the brain and has been genetically implicated in schizophrenia in two genetic studies. Mice with the gene encoding stathmin knocked out, so that they do not express this protein in the brain, show abnormal fear respon ...

                                               

Uroporphyrinogen III decarboxylase

Uroporphyrinogen III decarboxylase is a homodimeric enzyme PDB: 1URO ​ that catalyzes the fifth step in heme biosynthesis, which corresponds to the elimination of carboxyl groups from the four acetate side chains of uroporphyrinogen III to yield ...

                                               

USH2A

Usherin is a protein that in humans is encoded by the USH2A gene. This gene encodes a protein that Usherin contains laminin EGF motifs, the pentraxin domain, and many fibronectin type III motifs. Coded basement membrane-associated proteins may be ...

                                               

USP1

Ubiquitin carboxyl-terminal hydrolase 1 is an enzyme that in humans is encoded by the USP1 gene. This gene encodes a member of the ubiquitin-specific processing of the UBP family of proteases that is a deubiquitinating enzyme dub with his and CYS ...

                                               

USP48

Ubiquitin carboxyl-terminal hydrolase 48 is an enzyme that in humans is encoded by the USP48 gene. This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-termin ...

                                               

UTP-glucose-1-phosphate uridylyltransferase

UTP - glucose-1-phosphate uridylyltransferase also known as glucose-1-phosphate uridylyltransferase is an enzyme involved in carbohydrate metabolism. It synthesizes UDP-glucose from glucose-1-phosphate and UTP, i.e., glucose-1-phosphate + UTP ⇌ { ...

                                               

VAMP3

Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the ves ...

                                               

VAMP4

Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by th ...

                                               

VANGL2

The protein encoded by the VANGL2 gene is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or grou ...

                                               

VAV3

Guanine nucleotide exchange factor VAV3 is a protein that in humans is encoded by the VAV3 gene. This gene is a member of the genetic family of VAV. VAV proteins are guanine nucleotide exchange factors GEF family of Rho exhibition of GTPase, whic ...

                                               

VCAM-1

Vascular cell adhesion protein 1 also known as vascular cell adhesion molecule 1 or cluster of differentiation 106 is a protein that in humans is encoded by the VCAM1 gene. VCAM-1 functions as a cell adhesion molecule.

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Pino - logical board game which is based on tactics and strategy. In general this is a remix of chess, checkers and corners. The game develops imagination, concentration, teaches how to solve tasks, plan their own actions and of course to think logically. It does not matter how much pieces you have, the main thing is how they are placement!

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