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IGFBP1

Insulin-like growth factor-binding protein 1 also known as placental protein 12 is a protein that in humans is encoded by the IGFBP1 gene.

                                               

IGFBP3

Insulin-like growth factor-binding protein 3, also known as IGFBP-3, is a protein that in humans is encoded by the IGFBP3 gene. IGFBP-3 is one of six IGF binding proteins that have highly conserved structures and bind the insulin-like growth fact ...

                                               

IMPDH1

IMP dehydrogenase 1 acts as a homotetramer to regulate cell growth. IMPDH1 is an enzyme that catalyzes the synthesis of xanthine monophosphate XMP from inosine-5-monophosphate IMP. This is the rate-limiting step in the de novo synthesis of guanin ...

                                               

ING3

Inhibitor of growth protein 3 is a protein that in humans is encoded by the ING3 gene. The protein encoded by this gene is similar to ING1, of a tumor suppressor protein that can interact with ТР53, inhibit cell growth and induce apoptosis. This ...

                                               

INHBA

Inhibin, beta A, also known as INHBA, is a protein which in humans is encoded by the INHBA gene. INHBA is a subunit of both activin and inhibin, two closely related glycoproteins with opposing biological effects.

                                               

Insulin-induced gene 1 protein

Insulin induced gene 1, also known as INSIG1, is a protein which in humans is encoded by the INSIG1 gene. INSIG1 is short for insulin-induced gene 1, it is located on the 7th chromosome 7q36. This human gene encodes a transmembrane protein of 277 ...

                                               

Integrin beta 8

This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin com ...

                                               

INTS1

INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit POLR2A, MIM 180660 and mediates 3-prime end processing of small nuclear RNAs U1 RNU1, MIM 180680 and U2 RNU2, MIM 180690 ...

                                               

JAZF1

Juxtaposed with another zinc finger protein 1 also known as TAK1-interacting protein 27 or zinc finger protein 802 is a protein that in humans is encoded by the JAZF1 gene. Variants are associated with an increased risk of prostate cancer, an inc ...

                                               

KCND2

Potassium voltage-gated channel subfamily D member 2 is a protein that in humans is encoded by the KCND2 gene. It contributes to the cardiac transient outward potassium current, the main contributing current to the repolarizing phase 1 of the car ...

                                               

KCTD7

Potassium channel tetramerisation domain containing 7 is a protein in humans that is encoded by the KCTD7 gene. Alternative splicing results in multiple transcript variants.

                                               

KMT2E

This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia MLL family and encodes a protein with an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. Alternate transcr ...

                                               

Laminin, beta 1

Laminin subunit beta-1 is a protein that in humans is encoded by the LAMB1 gene. Laminins a family of extracellular matrix glycoproteins, are the major noncollagenous component of basement membrane. They were involved in a wide range of biologica ...

                                               

LANCL2

LanC-like protein 2 is a protein that in humans is encoded by the LANCL2 gene. It is a protein broadly expressed in the plasma a nuclear membranes of immune, epithelial and muscle cells and a potential therapeutic target for chronic inflammatory, ...

                                               

LAT2

Linker for activation of T-cells family member 2 is a protein that in humans is encoded by the LAT2 gene. This gene is one of the contiguous genes at 7q11.23 typically deleted in Williams syndrome, polysystemic pathology development. This gene co ...

                                               

LCHN

LCHN is a protein that in humans is encoded by the KIAA1147 gene located on chromosome 7. It is likely part of the tripartite DENN domain family of proteins that often function as Rab-GEFs to regulate vesicular trafficking. Both the mRNA and prot ...

                                               

LFNG

LFNG O -fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, also known as LFNG and Lunatic Fringe, is a human gene. This gene encodes a member of the glycosyltransferase superfamily. The encoded protein is a single-pass type II Golgi membrane ...

                                               

LHFPL3 (gene)

This gene is a member of the lipoma HMGIC fusion partner LHFP gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in one LHFP-like gene result in deafness in humans and mice, and a second ...

                                               

LIMK1

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or ...

                                               

LMBR1

Limb region 1 protein homolog is a protein that in humans is encoded by the LMBR1 gene. This gene encodes a member of the LMBR1-like membrane family protein. Another member of this family of proteins has been shown to be lipocalin transmembrane r ...

                                               

LMTK2

The LMTK2 enzyme belongs to both the protein kinase and the tyrosine kinase families. It contains N-terminus transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with ...

                                               

LRCH4

Leucine-rich repeat and calponin homology domain-containing protein 4 is a protein that in humans is encoded by the LRCH4 gene. This gene encodes a protein that contains leucine-rich repeats of LRR at its amino terminal and which is known to be i ...

                                               

LRRC4

Leucine-rich repeat-containing protein 4 is a protein that in humans is encoded by the LRRC4 gene. This gene considerably leads to negative regulation in primary brain tumors. The exact function of the protein encoded by this gene is unknown.

                                               

LRRN3

Leucine-rich repeat neuronal protein 3, also known as neuronal leucine-rich repeat protein 3, is a protein that in humans is encoded by the LRRN3 gene.

                                               

LSM5

U6 snRNA-associated Sm-like protein LSm5 is a protein that in humans is encoded by the LSM5 gene. And SM-like proteins were discovered in various organisms based on sequence homology with the family of cm SNRPD2 protein, MIM 601061. Sm-like prote ...

                                               

LSM8

U6 snRNA-associated Sm-like protein LSm8 is a protein that in humans is encoded by the LSM8 gene. This gene is a member of the LSM family and encodes a protein with a closed barrel shape, made up of five antiparallel beta-strands and alpha-helice ...

                                               

Macc1, met transcriptional regulator

MACC1 is a key regulator of the hepatocyte growth factor HGF-HGF receptor HGFR pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in col ...

                                               

MAGI2

Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 also known as membrane-associated guanylate kinase inverted 2 and atrophin-1-interacting protein 1 is an enzyme that in humans is encoded by the MAGI2 gene.

                                               

MALSU1

MALSU1 is a gene on chromosome 7 in humans that encodes the protein MALSU1. This protein localizes to mitochondria and is probably involved in mitochondrial translation or the biogenesis of the large subunit of the mitochondrial ribosome.

                                               

MCM7

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins MCM that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key com ...

                                               

Mesoderm-specific transcript homolog protein

Mesoderm-specific transcript homolog protein is a protein that in humans is encoded by the MEST gene. This gene encodes a member of the hydrolase fold family and isoform-specific imprinting. Loss of imprinting of the Gene was associated with cert ...

                                               

Metabotropic glutamate receptor 3

In humans, mGluR3 is encoded by the GRM3 gene on chromosome 7. At least five protein-coding isoforms are predicted based on genomic information. The mGluR3 protein is a seven-pass transmembrane protein.

                                               

Metabotropic glutamate receptor 8

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be ...

                                               

METTL2B

Methyltransferase-like protein 2B is an enzyme that in humans is encoded by the METTL2B gene. This gene is a member of a family of methyltransferases that share homology With, but distinct from, the Ubie family of methyltransferases. Alternative ...

                                               

MINDY4

The predicted molecular weight is 84.400 Daltons and pI is 6.465. pTARGET predicts the cellular location to be in the golgi apparatus with 93.9% confidence.

                                               

Motile sperm domain containing 3

This gene encodes a multi-pass membrane protein with a major sperm protein MSP domain. The deletion of a similar mouse gene is associated with defective cardiac development and neonatal lethality. Alternate transcriptional splice variants, encodi ...

                                               

MPLKIP

M-phase-specific PLK1-interacting protein is a protein that in humans is encoded by the MPLKIP gene. Patients with an inherited defect in both alleles of the gene suffer from trichothiodystrophy, a disease hallmarked by brittle hair and nails and ...

                                               

MPP6

MAGUK p55 subfamily member 6 is a protein that in humans is encoded by the MPP6 gene. Members of the peripheral membrane-associated kinases disodium guanylate, and disodium MAGUK family function in tumor suppression and receptor clustering by for ...

                                               

MTERF

Mitochondrial transcription termination factor, also known as MTERF, is a protein which in humans is encoded by the MTERF gene. This gene encodes a mitochondrial transcription termination factor. This protein participates in attenuating transcrip ...

                                               

Mucin 17

Mucin-17 is a protein that in humans is encoded by the MUC17 gene. Membrane Mucins, such as MUC17, function in epithelial cells to provide cytoprotection, maintain luminal structure, provide signal transduction, and also in conferring anti-adhesi ...

                                               

Muscarinic acetylcholine receptor M2

The muscarinic acetylcholine receptor M 2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor that in humans is encoded by the CHRM2 gene. Multiple alternatively spliced transcript variants have been desc ...

                                               

N-acyl phosphatidylethanolamine-specific phospholipase D

N-acyl phosphatidylethanolamine phospholipase D is an enzyme that catalyzes the release of N-acylethanolamine from N-acyl-phosphatidylethanolamine. This is a major part of the process that converts ordinary lipids into chemical signals like anand ...

                                               

NDUFA4

NDUFA4, mitochondrial complex associated is a protein that in humans is encoded by the NDUFA4 gene. The NDUFA3 protein is a subunit of NADH dehydrogenase, which is located in the mitochondrial inner membrane and is the largest of the five complex ...

                                               

Neuropeptide Y

Neuropeptide Y is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the central and peripheral nervous systems. NPY has been identified as the most abundant peptide present in the mammalian c ...

                                               

NME8

Thioredoxin domain-containing protein 3, also known as spermatid-specific thioredoxin-2, is a protein that in humans is encoded by the NME8 gene on chromosome 7.

                                               

NOD1

Nucleotide-binding oligomerization domain-containing protein 1 is a protein receptor that in humans is encoded by the NOD1 gene. It recognizes bacterial molecules and stimulates an immune reaction. NOD1 protein contains the activation domain casp ...

                                               

NOM1

Nucleolar protein with MIF4G domain 1 is a protein that in humans is encoded by the NOM1 gene. Proteins that contain MIF4G the middle of eIF4G MIM 600495) and / or MA3 Domains, such as NOM1, function in protein translation. These domains include ...

                                               

NPTX2

This gene encodes a member of the family of neuronal pentraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-met ...

                                               

NRCAM

Neuronal cell adhesion molecule is a protein that in humans is encoded by the NRCAM gene. Cams cell adhesion molecules are members of the superfamily of immunoglobulins. This gene encodes a neuronal cell adhesion molecules with multiple immunoglo ...

                                               

NSUN5

Putative methyltransferase NSUN5 is an enzyme that in humans is encoded by the NSUN5 gene. This gene encodes a protein with similarity to p120 NOL1, a 120-KDA proliferation associated nucleolar antigen that is a member of the evolutionary conserv ...

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Pino - logical board game which is based on tactics and strategy. In general this is a remix of chess, checkers and corners. The game develops imagination, concentration, teaches how to solve tasks, plan their own actions and of course to think logically. It does not matter how much pieces you have, the main thing is how they are placement!

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