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MYH1

Myosin-1, also known as striated muscle myosin heavy chain 1, is a protein that in humans is encoded by the MYH1 gene. This gene is most highly expressed in fast type IIX/D muscle fibres of vertebrates and encodes a protein found uniquely in stri ...

                                               

MYH3

Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains MYH and two pairs of nonidentical light chains. Thi ...

                                               

MYH10

Myosin-10 also known as myosin heavy chain 10 or non-muscle myosin IIB is a protein that in humans is encoded by the MYH10 gene. Non-muscle myosins are expressed in a wide variety of tissues, but NM-IIB is the only non-muscle myosin II isoform ex ...

                                               

MYL4

Atrial Light Chain-1, also known as Essential Light Chain, Atrial is a protein that in humans is encoded by the MYL4 gene. ALC-1 is expressed in fetal cardiac ventricular and fetal skeletal muscle, as well as fetal and adult cardiac atrial tissue ...

                                               

MYO1C

Myosin-Ic is a protein that in humans is encoded by the MYO1C gene. This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. Protein is located in cytoplasm, and one isoform with a unique N-T ...

                                               

Myocardin

Myocardin is a protein that in humans is encoded by the MYOCD gene. Myocardin in smooth muscle and cardiac muscle-specific transcription factor coactivator answer serum. When expressed ectopically in non-muscle cells, myocardin can induce smooth ...

                                               

NAGLU

This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides.

                                               

Netrin 1

Netrin-1 is a protein that in humans is encoded by the NTN1 gene. Netrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been, however, netrin is thought to be involved in Axon guidance and cell ...

                                               

Nitric oxide synthase 2 (inducible)

Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

                                               

NKIRAS2

Model organisms have been used in the study of NKIRAS2 function. A conditional knockout mouse line, called Nkiras2 tm1aEUCOMMWtsi was generated as part of the International Knockout Mouse Consortium program - a high-throughput mutagenesis project ...

                                               

NLGN2

Neuroligin-2 is a protein that in humans is encoded by the NLGN2 gene. This gene encodes a member of a family of neuronal cell surface proteins. The members of this family can act as a specific junction of the ligands for beta-neurexins and may b ...

                                               

NLK

Serine/threonine protein kinase NLK is an enzyme that in humans is encoded by the NLK gene. Its name is an abbreviation for Nemo-Like Kinase, Nemo being the Drosophila ortholog of the mammalian NLK gene. This enzyme is a member of the Mitogen-act ...

                                               

NLRP1

NLRP1 encodes NACHT, LRR, FIIND, CARD domain and PYD domains-containing protein 1 in humans. NLRP1 was the first protein shown to form an inflammasome. NLRP1 is expressed by a variety of cell types, which are predominantly hematopoietic. The expr ...

                                               

NME1

This gene NME1 was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase NDK exists as a hexamer composed of A encoded by this gene and B encoded by NME2 isoforms. Mutations in this gen ...

                                               

NPEPPS

Puromycin-sensitive amino peptidase also known as cytosol alanyl aminopeptidase or alanine aminopeptidase is an enzyme that in humans is encoded by the NPEPPS gene. It is used as a biomarker to detect damage to the kidneys, and that may be used t ...

                                               

NPLOC4

Model organisms have been used in the study of NPLOC4 function. A conditional knockout mouse line, called Nploc4 tm1aEUCOMMWtsi was generated as part of the International Knockout Mouse Consortium program - a high-throughput mutagenesis project t ...

                                               

NPTX1

NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system.

                                               

NT5C

5, 3-nucleotidase, cytosolic, also known as 5-deoxyribonucleotidase, cytosolic type or deoxy-5-nucleotidase 1, is an enzyme that in humans is encoded by the NT5C gene on chromosome 17. This gene encodes a nucleotidase that catalyzes the dephospho ...

                                               

Nucleoporin 85

Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes NPCs embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP85 is part of one such subcomplex, Nup107-160.

                                               

Nucleoporin 88

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the mai ...

                                               

OR1A1

Olfactory receptor 1A1 is a protein that in humans is encoded by the OR1A1 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR1A2

Olfactory receptor 1A2 is a protein that in humans is encoded by the OR1A2 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR1D2

Olfactory receptor 1D2 is a protein that in humans is encoded by the OR1D2 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR1D5

Olfactory receptor 1D5 is a protein that in humans is encoded by the OR1D5 gene. interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of ...

                                               

OR1E1

Olfactory receptor 1E1 is a protein that in humans is encoded by the OR1E1 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR1E2

Olfactory receptor 1E2 is a protein that in humans is encoded by the OR1E2 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR1G1

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors GPCR arising fr ...

                                               

OR3A1

Olfactory receptor 3A1 is a protein that in humans is encoded by the OR3A1 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR3A2

Olfactory receptor 3A2 is a protein that in humans is encoded by the OR3A2 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR3A3

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors GPCR arising fr ...

                                               

OR4D1

Olfactory receptor 4D1 is a protein that in humans is encoded by the OR4D1 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR4D2

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors GPCR arising fr ...

                                               

P70-S6 Kinase 1

Ribosomal protein S6 kinase beta-1, also known as p70S6 kinase, is an enzyme that in humans is encoded by the RPS6KB1 gene. It is a serine/threonine kinase that acts downstream of PIP3 and phosphoinositide-dependent kinase-1 in the PI3 kinase pat ...

                                               

PAFAH1B1

Platelet-activating factor acetylhydrolase IB subunit alpha is an enzyme that in humans is encoded by the PAFAH1B1 gene. The protein is often referred to as Lis1 and plays an important role in regulating the motor protein Dynein.

                                               

Pancreatic polypeptide

Pancreatic polypeptide is a polypeptide secreted by PP cells in the endocrine pancreas predominantly in the head of the pancreas. It consists of 36 amino acids and has molecular weight about 4200 Da. The function of PP is to self-regulate pancrea ...

                                               

PCGF2

The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group PcG gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in ...

                                               

PDK2

Pyruvate dehydrogenase kinase isoform 2 also known as pyruvate dehydrogenase lipoamide kinase isozyme 2, mitochondrial is an enzyme that in humans is encoded by the PDK2 gene. PDK2 is an isozyme of pyruvate dehydrogenase kinase.

                                               

PEDF

Pigment epithelium-derived factor also known as serpin F1, is a multifunctional secreted protein that has anti-angiogenic, anti-tumorigenic, and neurotrophic functions. Found in vertebrates, this 50 kDa protein is being researched as a therapeuti ...

                                               

Peripheral myelin protein 22

Growth arrest-specific protein 3, also called peripheral myelin protein 22, is a protein which in humans is encoded by the PMP22 gene. PMP22 is a 22 KDA transmembrane glycoprotein, consists of 160 amino acids and is mainly expressed in Schwann ce ...

                                               

PEX12

PEX12 is needed for protein import into peroxisomes. This gene belongs to the peroxin-12 family. Peroxins PEXs are proteins that are essential for the assembly of functional peroxisomes.

                                               

Phenylethanolamine N-methyltransferase

Phenylethanolamine N-methyltransferase is an enzyme found primarily in the adrenal medulla that converts norepinephrine to epinephrine. It is also expressed in small groups of neurons in the human brain and in select populations of cardiomyocytes.

                                               

Phosphatidylcholine transfer protein

Phosphatidylcholine transfer protein also known as StAR-related lipid transfer domain protein 2 is a specific intracellular phospholipid binding protein that can transfer phosphatidylcholine between different membranes in the cytosol. The people ...

                                               

Phosphatidylethanolamine N-methyltransferase

Phosphatidylethanolamine N-methyltransferase is a transferase enzyme which converts phosphatidylethanolamine to phosphatidylcholine in the liver. In humans it is encoded by the PEMT gene within the Smith–Magenis syndrome region on chromosome 17. ...

                                               

Phosphatidylinositol transfer protein, cytoplasmic 1

This gene encodes a member of the phosphatidylinositol transfer protein family. The encoded cytoplasmic protein plays a role in multiple processes including cell signaling and lipid metabolism by facilitating the transfer of phosphatidylinositol ...

                                               

PIGS (gene)

GPI transamidase component PIG-is an enzyme that in humans is encoded by the PIGS gene. This gene encodes a protein that is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol anchor is a glycolipid found on many blood cells and ...

                                               

PIGW

Glycosylphosphatidylinositol GPI is a complex glycolipid that anchors many proteins to the cell surface. PIGW acts in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol Murakami et al., 2003.

                                               

PIP4K2B

Phosphatidylinositol-5-phosphate 4-kinase type-2 beta is an enzyme that in humans is encoded by the PIP4K2B gene. The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo- ...

                                               

PKC alpha

Protein kinase C PKC is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be in ...

                                               

PLCD3

This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4.5-bisphosphate to generate the second messengers diacylglycerol and inositol 1.4.5-trisphosphate IP 3. Diacylglycerol and IP 3 media ...

                                               

PLD2

Phosphatidylcholine PC-specific phospholipases D PLDs catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coup ...

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Pino - logical board game which is based on tactics and strategy. In general this is a remix of chess, checkers and corners. The game develops imagination, concentration, teaches how to solve tasks, plan their own actions and of course to think logically. It does not matter how much pieces you have, the main thing is how they are placement!

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