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OPHN1

Oligophrenin 1 has 25 exons and encodes a Rho-GTPase-activating protein. The Rho protein are important mediators of intracellular signal transduction, which affects cell migration and cell morphogenesis.

                                               

OPN1LW

OPN1LW is a gene on the X chromosome that encodes for long wave sensitive opsin, or red cone photopigment. It is responsible for perception of visible light in the yellow-green range on the visible spectrum. The gene contains 6 exons with variabi ...

                                               

OR13H1

Olfactory receptor 13H1 is a protein that in humans is encoded by the OR13H1 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor ...

                                               

Otu deubiquitinase 5

This gene encodes a member of the OTU ovarian tumor domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune r ...

                                               

PAGE1

This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. Unlike the other gene family members, this gene does not encode an antigenic peptide. Nothing is presently known ab ...

                                               

PAK3

PAK3 is one of three members of Group I PAK family of evolutionary conserved serine/threonine kinases. PAK3 is preferentially expressed in neuronal cells and involved in synapse formation and plasticity and mental retardation.

                                               

PBDC1

CXorf26, also known as MGC874, is a well conserved human gene found on the plus strand of the short arm of the X chromosome. The exact function of the gene is poorly understood, but the polysaccharide biosynthesis domain that spans a major portio ...

                                               

PCTK1

The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells. This gene is thought to escape X inactivation. Tw ...

                                               

PDK3

Pyruvate dehydrogenase lipoamide kinase isozyme 3, mitochondrial is an enzyme that in humans is encoded by the PDK3 gene. It codes for an isozyme of pyruvate dehydrogenase kinase.The pyruvate dehydrogenase complex is a nuclear-encoded mitochondri ...

                                               

PFKFB1

6-phosphofructo-2-kinase/fructose-2.6-biphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2.6-biphosphatase enzymes. The enzyme form ...

                                               

PGRMC1

Progesterone receptor membrane component 1 is a protein which co-purifies with progesterone binding proteins in the liver and ovary. In humans, the PGRMC1 protein is encoded by the PGRMC1 gene. The sole biochemical function of PGRMC1 is heme-bind ...

                                               

PHEX

Phosphate-regulating neutral endopeptidase, X-linked also known as phosphate-regulating gene with homologies to endopeptidases on the X chromosome or metalloendopeptidase homolog PEX is an enzyme that in humans is encoded by the PHEX gene. This g ...

                                               

PI-PLC X domain-containing protein 1

PI-PLC X domain-containing protein 1, also known as Phosphatidylinositol-specific phospholipase C, X domain containing 1, is an enzyme which in humans is encoded by the PLCXD1 gene. The gene coding for this protein is located in the pseudoautosom ...

                                               

PIGA

Phosphatidylinositol N-acetylglucosaminyltransferase subunit A is the catalytic subunit of the phosphatidylinositol N-acetylglucosaminyltransferase enzyme, which in humans is encoded by the PIGA gene. This gene encodes a protein required for the ...

                                               

PIM2 (gene)

Serine/threonine-protein kinase Pim-2 is an enzyme that in humans is encoded by the PIM2. PIM2 or Proviruses integration of Moloney virus 2 is serine / threonine kinase that plays an important role in cell growth, proliferation, apoptosis and the ...

                                               

PIR (gene)

Pirin is a protein that in humans is encoded by the PIR gene. This gene encodes a member of the cupin superfamily. The encoded protein is swallowed, containing nuclear protein expressed in all body tissues and concentrates in dot-like subnuclear ...

                                               

PLXNB3

Model organisms have been used in the study of PLXNB3 function. A conditional knockout mouse line called Plxnb3 tm1aKOMPWtsi was generated at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen ...

                                               

POU3F4

POU domain, class 3, transcription factor 4 is a protein that in humans is encoded by the POU3F4 gene found on the X chromosome. POU3F4 is involved in the patterning of neural tube and supraopticus and paraventricular nuclei of the hypothalamus i ...

                                               

PPP2R3B

Protein phosphatase 2 formerly named type 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structur ...

                                               

PQBP1

Polyglutamine-binding protein 1 is a protein that in humans is encoded by the PQBP1 gene. Polyglutamine binding protein-1 is a highly conserved nuclear protein expressed in mesodermal tissues and nuclear. The molecular role of PQBP1 in embryonic ...

                                               

PRDX4

The protein encoded by this gene is an antioxidant enzyme of the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with ...

                                               

PRKX

This gene encodes a serine threonine protein kinase that has similarity to the catalytic subunit of cyclic AMP dependent protein kinases. The encoded protein is developmentally regulated and may be involved in renal epithelial morphogenesis. This ...

                                               

Properdin

Properdin is the only known positive regulator of complement activation that stabilizes the alternative pathway convertases. It is found in the blood serum of more complex animals.

                                               

Proprotein convertase subtilisin/kexin type 1 inhibitor

The protein encoded by this gene functions as an inhibitor of prohormone convertase 1, which regulates the proteolytic cleavage of neuroendocrine peptide precursors. The proprotein is further processed into multiple short peptides. Differential e ...

                                               

PRR32

PRR32 is a protein that in humans is encoded by the CXorf64 gene. It was also found that the homologs of the PRR32 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat. It was also found through ncbi that 82 organisms have ort ...

                                               

Rab escort protein 1

Rab escort protein 1 also known as rab proteins geranylgeranyltransferase component A 1 is an enzyme that in humans is encoded by the CHM gene.

                                               

RAB33A

Ras-related protein Rab-33A is a protein that in humans is encoded by the RAB33A gene. The protein encoded by this gene belongs to the small GTP-ASE superfamily, RAB family. This GTP-binding protein and may be involved in vesicle transport.

                                               

RAB39B

Ras-related protein Rab-39B is a protein that in humans is encoded by the RAB39B gene. This gene encodes a member of the family of RAB proteins. RAB proteins are small GTPase who are engaged in vesicular transport.

                                               

RAI2

Retinoic acid-induced protein 2 is a protein that in humans is encoded by the RAI2 gene. Retinoic acid plays an important role in development, cellular growth and differentiation. The specific function of this intronless, retinoic acid-induced ge ...

                                               

RBBP7

This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The ...

                                               

RBM3

This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif RRM domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Al ...

                                               

RBM10

RNA-binding protein 10 is a protein that in humans is encoded by the RBM10 gene. The protein encoded by this gene contains RNA recognition motif found in various RNA-binding proteins, including various hnRNP proteins regulation of alternative spl ...

                                               

RBMX

This gene belongs to the RBMY gene family which includes candidate Y chromosome spermatogenesis genes. This gene, an active X chromosome homolog of the Y chromosome RBMY gene, is widely expressed whereas the RBMY gene evolved a male-specific func ...

                                               

RENBP

N-acylglucosamine 2-epimerase is an enzyme that in humans is encoded by the RENBP gene. The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a domain ...

                                               

REPS2

The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its exp ...

                                               

Retinitis pigmentosa GTPase regulator

This gene encodes a protein with a series of six RCC1-like domains RLDs, characteristic of the highly conserved guanine nucleotide exchange factors. Mutations in this gene have been associated with X-linked retinitis pigmentosa XLRP. Multiple alt ...

                                               

Retinoschisin

Retinoschisin also known as X-linked juvenile retinoschisis protein is a lectin that in humans is encoded by the RS1 gene. It dissolves the cell-surface protein that plays an important role in the maintenance of the retina, where it is expressed ...

                                               

Retrotransposon Gag like 3

This gene is a member of a family of gag-related retrotransposon genes. These genes appear to have lost the ability to retrotranspose, however, their open reading frames have remained intact, which may indicate that these genes have acquired new ...

                                               

RHOXF2

Rhox homeobox family, member 2 also known as paired-like homeobox protein is a protein in humans that is encoded by the RHOXF2 gene. RHOXF2 contains glutamine-rich N-Terminus, and the homeodomain and the Proline-rich c-Terminus.

                                               

Ribose-phosphate diphosphokinase

Ribose-phosphate diphosphokinase is an enzyme that converts ribose 5-phosphate into phosphoribosyl pyrophosphate. It is classified under EC 2.7.6.1. The enzyme involved in the synthesis of nucleotides, purines and pyrimidines, cofactors nad and N ...

                                               

RNF12

The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be a ubiquitin protein ligase that targets LIM domain binding 1 LDB1/CLIM, and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-r ...

                                               

RNF128

E3 ubiquitin-protein ligase RNF128 is an enzyme that in humans is encoded by the RNF128 gene. The protein encoded by this gene is a type I transmembrane protein that is localized in endocytosis way. This protein contains a ring zinc finger motif ...

                                               

RP2 (gene)

The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration ma ...

                                               

RPS4X

40S ribosomal protein S4, X isoform is a protein that in humans is encoded by the RPS4X gene. Ribosomes, the organelles that catalyze protein synthesis, consist of small units of the 40-ies and 60-ies of the large subunit. Together these subunits ...

                                               

RPS6KA3

This gene encodes a member of the RSK ribosomal S6 kinase family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase M ...

                                               

RPS6KA6

Ribosomal protein S6 kinase, 90kDa, polypeptide 6 is a protein in humans that is encoded by the RPS6KA6 gene. This gene encodes a member of the family of ribosomal S6 kinase Serine-threonin protein kinases, which are regulated by growth factors. ...

                                               

S100G

S100 calcium-binding protein G is a protein that in humans is encoded by the S100G gene. This gene encodes calbindin D9K, a vitamin D-dependent calcium-binding protein. This cytosolic protein belongs to a family of calcium-binding proteins that i ...

                                               

SAT1 (gene)

Spermidine/spermine N1-acetyltransferase SPD/SPM acetyltransferase is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the N1-acetylation of spermidine and spermine and, by the successive activity of polyamine ...

                                               

SEPT6

This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its ...

                                               

SH2D1A

SH2 domain–containing protein 1A is a protein that in humans is encoded by the SH2D1A gene. It is often called SLAM-associated protein, where "SLAM" refers to signaling lymphocytic activation molecules. It is a SH2 domain–containing molecule that ...

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Pino - logical board game which is based on tactics and strategy. In general this is a remix of chess, checkers and corners. The game develops imagination, concentration, teaches how to solve tasks, plan their own actions and of course to think logically. It does not matter how much pieces you have, the main thing is how they are placement!

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